Spectrum: Local Antimicrobial Stewardship, for Markham Stouffville Hospital

IV to PO Stepdown Options

Option 1

Trimethoprim-Sulfamethoxazole 1 DS tab po bid

PLUS

Metronidazole 500 mg po bid

Option 2

Cephalexin 500 mg po qid

PLUS

Metronidazole 500 mg po bid

Option 3

Amoxicillin-clavulanate 875 mg po bid