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If intended course of gentamicin/tobramycin is greater than 72 hrs, levels need to be ordered as follows:
For Once-Daily Dosing
Order levels 3 and 6 hrs post-dose
Pharmacokinetic Targets Extrapolated Cmax = 16-25 mg/L; Drug-Free Interval (DFI) greater than 4 hrs
For Traditional Multiple Daily Dosing (i.e. q8h)
Target Levels for UTI Trough 0.6-2 mg/L; Peak 3-5 mg/L
Target Levels for Pyelonephritis Trough 0.6-2 mg/L; Peak 5-7 mg/L
