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Pathogens
Antimicrobials
Ceftriaxone 50-75 mg/kg/day IV in 1 to 2 divided doses. Max 2g/day
Cefotaxime should be used instead of ceftriaxone if hyperbilirubinemia is present or if patient is receiving calcium-containing IV solutions.
AND
Metronidazole 10 mg/kg IV/PO q8h Max 4g/day IV; 2g/day PO
ALTERNATIVELY, CONSIDER
Piperacillin-Tazobactam
1 Month to Less Than 6 months 80 mg piperacillin/kg IV q6h
Over 6 Months 100 mg piperacillin/kg IV q6h
