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Guidelines
Pathogens
Antimicrobials
Treatment of prosthetic valve endocarditis (PVE) is more difficult than treatment of native valve endocarditis (NVE) and may require surgical replacement of the prostheses in addition to antibiotic therapy.
Common Pathogens
Vancomycin
PLUS
Cefepime 2 gm IV every 8 hr
Gentamicin 1 mg/kg IV every
8 hr
At least 6 wks