Spectrum: Local Antimicrobial Stewardship, for Bakersfield Memorial Hospital

Cefepime

C. diff Risk

High

Oral Bioavailability

NA

Approximate Cost

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

General Spectrum of Activity

Antibiogram Data

Dosing

Renal

Adult

2 g every 8-12 hr

Pediatric

General Information

Common Usage

Common Usage

Broad spectrum antimicrobial with gram positive and gram negative coverage including Pseudomonas.

Used especially nosocomial infections involving resistant organisms

Drug Monitoring

Drug Monitoring

Lab

  • monitor renal function

Clinical

  • Hypersensitivity

Adverse Effects

Adverse Effects

  • Allergy (immediate & delayed)

  •  Positive Coombs

  •  GI effects/Diarrhea

Pharmacology

Pharmacology

Antimicrobial class: 4th generation Cephalosporin

Pregnancy category: B

Average serum half life: 2 hours

Urine penetration: Therapeutic

Lung penetration: Therapeutic

CSF penetration: Therapeutic

Biliary penetration: Moderate