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Antimicrobials
Elevation of the affected area is recommended
Draw a line around the margins of the infection with a marker to better monitor day-to-day changes
Cefazolin 1 g IV every 8 hr
May Consider Adding
Vancomycin
*If concern for abscess or IVDU
Cellulitis often appears to get worse within the first 24 hours of antibiotics despite adequate therapy. If pain is stable or improving, continue recommended antibiotics.
At 72 hours, if 20% resolution of erythema, switch to PO and evaluate for discharge