Spectrum: Local Antimicrobial Stewardship, for NYC Department of Health

Ampicillin-Sulbactam

C. diff Risk

Medium

Oral Bioavailability

NA

Approximate Cost

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

General Spectrum of Activity

Antibiogram Data

Dosing

Adult

1.5-3 g IV every 6 hr

Renal

General Information

Common Usage

Common Usage

  • Skin and soft tissue infections

  • Polymicrobial infections of the respiratory tract or abdomen

Drug Monitoring

Drug Monitoring

Lab
In patients with preexisting hepatic impairment, periodic hepatic funtion monitoring

Clinical
Hypersensitivity reactions

Adverse Effects

Adverse Effects

  • Allergy/Skin rash

  • Diarrhea

  • Pain at injection site/phlebitis

Major Interactions

Major Interactions

Allopurinol - Increased rash

Pharmacology

Pharmacology

Antimicrobial class: Aminopenicillin

Pregnancy category: B

Average serum half life: 1 hour