Spectrum: Local Antimicrobial Stewardship, for Eastern Health

Necrotizing Pancreatitis Duration of Therapy

Recommended Duration

None

Antibiotic prophylaxis not recommended in absence of infection

Pancreatitis Management

Additional Notes

  • The data regarding reserving antimicrobials for pancreatitis with clear evidence of infection is supported by robust RCTs that show no impact on outcome

  • Adapted from AMMI Canada Position Statement on the Appropriate Duration of Antimicrobial Therapy (2018)

More Information

References
  1. Mazuski JE et al. The Surgical Infection Society revised guidelines on the management of intraabdominal infection. Surgical Infections, 18:1-76. 2017
  2. Wittau M et al. Systematic review and meta-analysis of antibiotic prophylaxis in severe acute pancreatitis. Scand J Gastroenterol 2011;46:261-270
  3. Villatoro E et al. Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis. Cochrane Database Syst Rev 2010;Issue 5:CD002941