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Antimicrobials
Antibiotics may not prevent complications, speed recovery or reduce recurrent diverticular disease in patients with uncomplicated, CT-proven diverticulitis.
If evidence of complications or peridiverticular abscess, consider the following for empiric antimicrobial therapy.
5-7 days
Ceftriaxone 1g IV q24h (can be given IM if no IV access)
AND
Metronidazole 500mg PO/IV q12h
Amoxicillin-clavulanate 500mg PO TID
Levofloxacin 750 mg PO/IV q24h