Rapid Diagnostic Tests

Typical Gram-positive Bacteria

Streptococcus pneumoniae

IV

Ampicillin-sulbactam
Ceftriaxone

PO

Amoxicillin-clavulanate

Typical Gram-negative Bacteria

Haemophilus influenzae, Moraxella catarrhalis

IV

Ampicillin-sulbactam
Ceftriaxone

PO

Amoxicillin-clavulanate

Atypical Bacteria

Legionella spp

IV

Levofloxacin
Azithromycin

PO

Levofloxacin
Azithromycin

Chlamydia (Chlamydophila) pneumoniae, Mycoplasma pneumoniae

IV

Azithromycin
Doxycycline

PO

Azithromycin
Doxycycline

Staphylococcus aureus

MSSA

IV

Nafcillin
Cefazolin

PO

Dicloxacillin
Cephalexin

MRSA

IV

Vancomycin
Linezolid

PO

Linezolid

Enterobacteriaceae

Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Proteus mirabilis

IV

Ceftriaxone

PO

NA

Other Enterobacteriaceae (with potential chromosomal AmpC production)

Enterobacter cloacae, Klebsiella (formerly Enterobacter) aerogenes, Serratia marcescens

IV

Cefepime

PO

NA

Non-Lactose-Fermenting Gram-negative Bacteria

Pseudomonas aeruginosa, Acinetobacter baumannii

IV

Cefepime
Piperacillin-tazobactam

PO

NA