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Guidelines
Pathogens
Antimicrobials
Specific therapy will be guided by susceptibility testing.
Treat 7 days if uncomplicated.
Catheter removal indicated, especially if drug-resistant GNB or Pseudomonas.
If catheter salvage attempted (not recommended), can attempt Antimicrobial Lock Therapy in addition to systemic therapy.
Antimicrobial Lock Therapy
Antimicrobial lock therapy involves instilling a high concentration of an antibiotic or other chemical (i.e. 70% ethyl alcohol) into the catheter lumen and letting it dwell.
Consultation with Infectious Diseases or an Antimicrobial Stewardship pharmacist is recommended.
