Infected Necrotizing Pancreatitis

IV therapy usually required

ID consult highly recommended

If source control achieved (e.g. pancreatic debridement), 14 days post-op may be adequate

Therapy ideally should be based on culture results

Empiric therapy can be initiated before guided aspiration or if aspiration cannot be obtained

Discontinue antibiotics if necrosis is found to be sterile

Strong evidence also exists for Moxifloxacin

Consider adding antifungals if candida risk factors present (see Candida in IAI below)

Enteral nutrition vs. TPN has been shown to decrease infectious complications