Spectrum: Local Antimicrobial Stewardship, for Yangon Children's Hospital

Special Circumstances

First-Line Treatment

Abacavir (ABC) 8 mg/kg/dose, twice per day (max: 300mg/dose)

For age <16 years or weight <37.5kg

OR

Zidovudine (AZT) 180-240 mg/m²/dose, twice per day (max: 300mg/dose)

Drug doses should be calculated according to body surface area

AND

Lamivudine (3TC) twice per day (max: 150mg/dose)

  • Age <30 days: 2 mg/kg/dose

  • Age >30 days: 4 mg/kg/dose

  • Weight >50kg: 150 mg

AND

Raltegravir (RAL) 1.5 mg/kg/dose

  • Neonates ≥37wks and ≥2kg: OD

  • Infants/children >3kg to <20kg: BD