Spectrum: Local Antimicrobial Stewardship, for Yangon Children's Hospital

Adolescent Alternative 3

First-Line Treatment

Abacavir (ABC) 8 mg/kg/dose, twice per day (max: 300mg/dose)

For age <16 years, or weight <37.5kg

AND

Lamivudine (3TC) twice per day (max: 150mg/dose)

  • Age <30 days: 2 mg/kg/dose

  • Age >30 days: 4 mg/kg/dose

  • Weight >50kg: 150 mg/kg/dose

OR

Emtricitabine (FTC) once per day (max: 200mg/dose)

  • Liquid: 6 mg/kg

  • Capsule: 200mg

AND

Efavirenz

(EFV) once per day (max: 600mg)

  • Liquid: 19.5 mg/kg

  • Capsule/tablet: 15 mg/kg

Second-Line Treatment (If Failing First-Line Regimen)

AZT + 3TC + ATV/r (or LPV/r or DRV/r or DTG)

RAL + LPV/r