Opportunistic Infection Prevention

Vaccines

HIV-infected children should be protected from vaccine-preventable diseases

Most vaccines recommended for routine use can be administered safely to HIV-exposed or HIV-infected children

Please refer to 'recommended immunization schedule of HIV-exposed or HIV-infected children' in MPS

Co-Trimoxazole Prophylaxis

  • Co-trimoxazole prophylaxis is recommended for HIV-exposed infants from 4-6 weeks of age

  • It should be continued until HIV infection has been excluded by an age-appropriate HIV test to establish final diagnosis at least 3 months after complete cessation of breastfeeding

  • Co-trimoxazole prophylaxis is recommended for infants, children, and adolescents with HIV, irrespective of clinical and immune conditions

  • Co-trimoxazole prophylaxis may be discontinued for children ≥5 years of age who are:

    • Clinically stable, AND/OR
    • Virally suppressed on ART for at least 6 months and with a CD4 count >350 cells/mm³