Spectrum: Local Antimicrobial Stewardship, for Yangon Children's Hospital

HACEK/Vancomycin Resistant/Intolerant

Possible Pathogens

HACEK Group

Recommended Treatment

Cefotaxime 200 mg/kg/day (Max. 12g daily) IV every 6hrs

OR

Ceftriaxone 100 mg/kg/day (Max. 4g) IV every 12hrs

OR

Ampicillin-sulbactam 200-300 mg/kg/day (Max. 12g) IV every 4-6hrs

Alternative Treatment

Ampicillin 200-300 mg/kg/day (Max. 12g) IV every 4-6hrs

AND ONE OF

Gentamicin 3-6 mg/kg/day IV every 8hrs

OR

Amikacin 15 mg/kg/day IV every 8-12hrs