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Guidelines
Pathogens
Antimicrobials
Vancomycin (Dosing per pharmacy)
CHANGE TO
Cloxacillin 2g IV q4h if susceptible.
OR
Cefazolin 2g IV q8h if susceptible.
Infectious Diseases consult is strongly advised for all patients with Staphylococcus aureus bloodstream infection.
A thorough search for metastatic sites of infection should be considered in all patients with S. aureus bloodstream infection
Remove central lines. Relapse rates are unacceptably high with line retention.
Vancomycin is inferior to cloxacillin or cefazolin for treatment of MSSA. Do not choose vancomycin solely due to convenience of dosing (e.g. in hemodialysis patients).
All patients with S. aureus bacteremia should have an echocardiogram to rule out infective endocarditis.
