Spectrum: Local Antimicrobial Stewardship, for CHEO-OCTC

Appendicitis - Complicated

Note

Ensure intra-operative cultures are taken.

Infection Prevention and Control

Routine Practices

Most Likely Pathogens

E. coli

Other Enterobacteriaceae

Anaerobes

Streptococcus sp. (e.g S. anginosus)

Empiric Antimicrobials

MetroNIDAZOLE IV

PLUS

Tobramycin IV

PLUS

Ampicillin IV

Usual Duration

5 days

Longer duration of therapy and drainage is recommended if there is presence of an intra-abdominal abscess.