Spectrum: Local Antimicrobial Stewardship, for CHEO-OCTC

Tobramycin

C. diff Risk

Low

Oral Bioavailability

NA

Approximate Cost

NA

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

General Spectrum of Activity

Antibiogram Data

Dosing

Pediatric

Neonatal

General Information

Drug Monitoring

Drug Monitoring

NOTE: For frequency adjustment due to renal dysfunction, consult clinical pharmacist.

  • Baseline serum creatinine. If normal and stable, repeat once weekly.

  • Recommended tobramycin level(s) as above. Once targeted levels achieved and serum creatinine stable, repeat once weekly.

  • Audiology consult recommended if IV aminoglycoside therapy is expected to continue for greater than 14 days. Repeat every 7 days.