Amoxicillin

C. diff Risk

Low

Oral Bioavailability

Excellent

Approximate Cost

$0.50/day

Dosing

500-1000mg po TID

General Information

Common Usage

Therapy of Streptococcal, Enterococcal infections as well as susceptible gram negative infections.

Commonly used for upper respiratory infections and Urinary tract infection

Adverse Effects

Allergy/rash (immediate or delayed), cytopenias.

Note EBV related rash

Major Interactions

Allopurinol - increased rash

Pharmacology

Antimicrobial class: Aminopenicillin

Pregnancy category: B

Average serum half life: 1.0

Biliary penetration: Therapeutic

CSF penetration: Moderate

Lung penetration: Therapeutic

Urine penetration: Therapeutic