Spectrum: Local Antimicrobial Stewardship, for AHS Calgary Zone

Gentamicin Synergy

C. diff Risk

Low

Oral Bioavailability

NA

Approximate Cost

$10-30/d

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

Dosing

Adult

Refer to Gentamicin

Renal

General Information

Common Usage

Common Usage

Used synergistically with an additional agent in infections such as enterococcal endocarditis and staphylococcal prosthetic valve endocarditis.

Drug Monitoring

Drug Monitoring

Refer to Gentamicin

Adverse Effects

Adverse Effects

Refer to Gentamicin

Major Interactions

Major Interactions

Refer to Gentamicin

Additional Information

Additional Information

Refer to Gentamicin

Pharmacology

Pharmacology

Antimicrobial class: Aminoglycoside

Pregnancy category: D

Average serum half life: 2.0

Biliary penetration: Moderate

CSF penetration: Poor

Lung penetration: Therapeutic

Urine penetration: Therapeutic