Medium
lots $
Reserved for highly resistant infections or when significant allergies restrict other options and when there is documented susceptibility
Associated with more treatment failures than alternatives and excess mortality - Black Box Warning
Avoid or use with caution in patients with tetracycline reactions
GI side effects very prominent with significant nausea and vomiting
Tetracycline related adverse events: photosensitivity, acute pancreatitis
Rash, abnormal liver enzymes
Requires Infectious Disease consultation
Documented safety concerns in bacteremia especially
Antimicrobial class: Tetracycline derivative
Pregnancy category: D
Average serum half life: 42.0
Biliary penetration: Therapeutic
Lung penetration: Therapeutic
