Environmental (soil, water) organism as well as human/animal digestive tract
Associated with penetrating wounds with environmental exposure
Gas gangrene/Clostridial myonecrosis
Necrotizing skin and soft tissue infection
Intra-abdominal abscess
Fatal bacteremia with massive exotoxin-mediated hemolysis
Foodborne self-limited gastrointestinal illness
Surgical debridement of devitalized tissue crucial
IVIG and hyperbaric oxygen may be considered but lack of rigorous studies to support routine use
