For invasive infections, prefer ceftriaxone as empiric therapy until susceptibilities provided - then use ampicillin

• Second and third generation cephalosporins

• Amoxicillin-clavulanate

• Fluoroquinolones

• Clarithromycin/azithromycin

• Doxycycline

Variable susceptibility to:

• Amoxicillin/ampicillin (via beta-lactamase)

• TMP-SMX

Resistant to first generation cephalosporins