Low
Good (70 to 90%)
<$
Treatment
Pharyngitis, due to Group A streptococcus
Otitis media, acute (AOM)
Pneumonia, community acquired
Skin and soft tissue infections, due to susceptible organisms
Urinary tract infections, due to susceptible organisms
Exit-site or tunnel infections in patients with peritoneal dialysis catheters
Combination therapy of Helicobacter pylori
Anthrax
Prophylaxis
Pneumococcal infection in sickle cell or asplenic patients
UTI
Postexposure prophylaxis of anthrax
Bacterial endocarditis in high risk patients undergoing dental treatment
Peritonitis in PD patients undergoing dental treatment
Allopurinol: May enhance the potential for allergic or hypersensitivity reactions to Amoxicillin
Tetracyclines: May diminish the therapeutic effect of Penicillins
Antimicrobial class: Aminopenicillin, beta-lactam
Pregnancy category: B
Average serum half life: Neonates, full-term: 3 to 4 hours
Infants and children: 1 to 2 hours
Biliary penetration: Detectable levels but lower than serum
CSF penetration: Poor penetration, except when meninges inflamed (14%)
Lung penetration: Good penetration
Urine penetration: Excreted in the urine
Route of Elimination: Renal excretion (60% unchanged drug)
Comments: Amoxicillin is the PO equivalent of ampicillin
