Microbiology

These are common colonizers in diabetic foot ulcers, especially when identified on sub-optimally collected specimens

Expanding antimicrobial coverage to include Pseudomonas or Enterococcus when found on culture is only necessary if patient is failing initial empiric regimen

Deep tissue involvement increases risk of gram negative bacilli

Necrotic, gangrenous, or foul-smelling wounds may involve mixed anaerobes