Spectrum: Local Antimicrobial Stewardship, for Fraser Health

Colistin

Restricted
Restricted

C. diff Risk

Low

Oral Bioavailability

NA

Approximate Cost

Dosing

Adult

ALL DOSING IS FOR COLISTIN BASE
Loading dose: 4 mg/kg IV once (use lower of ideal or actual body weight)
Maintenance dose: 150 mg IV q12h

Renal

General Information

Common Usage

Common Usage

IV Colistin should generally be used in combination therapy (meropenem or imipenem). Infectious Diseases consultation recommended.

Additional Information

Additional Information

Colistin equivalency conversion:
30 mg colistin base activity = 80 mg colistimethate = 1 million IU colistin