Spectrum: Local Antimicrobial Stewardship, for Fraser Health

Meropenem

Restricted
Restricted

C. diff Risk

Medium

Oral Bioavailability

NA

Approximate Cost

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

General Spectrum of Activity

Antibiogram Data

Dosing

Adult

High dose: 2000 mg IV q8h

Standard dose: 500 mg IV q6h

Renal

General Information

Adverse Effects

Adverse Effects

Immediate and delayed-type allergy

GI disturbanceCytopenias, positive Coombs

Liver enzyme abnormalities

Major Interactions

Major Interactions

Valproic acid - carbapenems decrease valproate levels and may decrease seizure threshold

Pharmacology

Pharmacology

Antimicrobial class: carbapenem

Pregnancy category: B