Low
Excellent
Restricted to infections caused by gram positive organisms that are resistant to vancomycin or in patients intolerant to vancomycin.
CBC at least once/week
Visual testing for therapy >3mo or if symptoms develop on therapy
Myelosuppression (usually after 2 weeks therapy) - reversible
Peripheral/optic neuropathy with prolonged courses
Serotonin syndrome
Rash
Elevated liver enzymes
Lactic acidosis
SSRI and other serotonergics/MAOIs - increased risk of serotonin syndrome
Rifampin decreases linezolid levels
