Use nitrofurantoin for UTI only
Variable activity
Ampicillin-sulbactam (65% susceptible)
Cefazolin/cephalexin - MIC breakpoints for determining susceptibility in urine vs other sources are different. E. coli 93% susceptible for urine isolates but poor option for pyelonephritis and systemic illnesses as only 52% susceptible by testing of blood culture isolates.
