MSSA

Anti-staphylococcal penicillins (i.e. nafcillin) and cephalosporins (i.e. cefazolin) are optimal agents for intravenous therapy of MSSA infections. Beta-lactams are preferred but if true allergy, alternative options include TMP-SMX, tetracyclines or for serious infections vancomycin.

Variable susceptibility to:

•  Clindamycin

MRSA

Susceptible to:

• Vancomycin

• Daptomycin (restricted to ID)

• Linezolid (restricted to ID)

• TMP-SMX

• Tetracyclines

Variably susceptible to:

• Clindamycin