Gram negative

•  Susceptible Enterobacteriaceae including ESBL producers

•  Pseudomonas aeurginosa

•  M. catarrhalis

•  H. influenzae

Other

•  Synergistic activity against Staphylococci and Enterococci

•  Some Mycobacteria spp

Does not cover

•  Most gram positives as monotherapy

•  Anaerobes

•  Atypicals