EAEC, EPEC, ETEC, EIEC

Abdominal cramps and watery diarrhea within 16-72 hours, can be prolonged

International travel, infantile diarrhea in developing countries

Enteroinvasive E. coli cause gastroenteritis indistinguishable from other bacterial pathogens.

Limited data in EAEC , EPEC, EIEC. Many patients recover without antimicrobial therapy and antimicrobial therapy is not routinely suggested.
Patients with severe or prolonged illness, or those with immunocompromise may benefit from treatment.

Antibiotics have been shown to shorten the duration of illness in ETEC and are generally indicated for moderate to severe diarrhea (>4 stools/day, fever, or blood or pus in stool) or for immunocompromised hosts