Clostridium difficile Infection (CDI)

More than 3 watery, loose, or unformed stools within 24 hours; lab findings may include leukocytosis and elevated creatinine

Rare < 2yrs age; up to 40% of children <1yr test positive

Recent antibiotic use, especially broad spectrum agents

If Clostridium difficile is suspected, order the C. difficile toxin assay

Discontinue antibiotics if possible