Nosocomial acquired pneumonia

Most likely pathogens

Duration of therapy

7-10 days

Suggested regimen

Ceftriaxone 50-75 mg/kg/dose IV q24h
Maximum: 2 grams/dose

OR

Piperacillin-tazobactam 240-300 mg/kg/24h IV divided q6-8h
(dosing based on piperacillin component)
Maximum:
4 grams/doseOR 16 grams/24h

Penicillin allergy

Ceftriaxone 50-75 mg/kg/dose IV q24h
Maximum: 2 grams/dose