Atypical mycobacterial

Most likely pathogen

Atypical mycobacterium (non-TB)

Note

Excision usually curative

Clarithromycin monotherapy may result in rapid resistance therefore 2 agents ALWAYS recommended. If intolerance to Clarithromycin, Azithromycin may be used in its place

Duration of therapy

3-6 months or until symptoms resolve if excision not curative

Suggested regimen

Clarithromycin 7.5 mg/kg/dose PO BID
Maximum: 1 gram/24h

AND

Rifampin 10-20 mg/kg/24h PO divided daily- BID
Maximum: 600 mg/24h

OR

Ethambutol 20-25 mg/kg/dose PO daily
Maximum: 1 gram/dose