Spectrum: Local Antimicrobial Stewardship, for IWK Health Centre

3 months of age to 12 years of age

Most likely organism

Herpes simplex virus (HSV)

Duration of therapy

21 days

Suggested regimen

Acyclovir 10-15 mg/kg/dose IV q8h

Note: Doses as high as 20 mg/kg/dose IV
may be used but are associated with a higher incidence of nephrotoxicity