AmpC - Organisms that produce AmpC beta-lactamase
General Susceptibility
Intrinsic resistance to Ampicillin and lower generation cephalosporins. With exposure to beta-lactams, induction or de-repression can occur and confer resistance to third generation cephalosporins
Susceptible to carbapenems
Usually susceptible to fluoroquinolones, TMP-SMX, and aminoglycosides which are appropriate targeted therapy options
Using non-carbapenem beta-lactams (i.e. Piperacillin/tazobactam, Ceftriaxone) when reported as susceptible likely reasonable for SIMPLE infections requiring SHORT duration.