Humans are the reservoir - fecal-oral transmission.
Increased prevalence in developing countries.
Highest prevalence South Asia
Fever in Returning Traveler
Enteric fever
FUO
Bacteremia
Intra-abdominal abscess
Meningitis
Endovascular infection including endocarditis
Very high rates of FQ resistance in Indian Subcontinent
Vaccination only prevents ~75% of disease
Chronic carriage associated with gallbladder disease - think "Typhoid Mary"
Notify Medical Officer of Health (Reportable)
