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Guidelines
Pathogens
Antimicrobials
Medium
Excellent
IV-15$
Renally cleared, requires dosage adjustment with changes in renal function. Consult a pharmacist for renal dosing.
Community acquired lower respiratory tract infections.
Allergy (immediate & delayed)
Positive Coombs
Cytopenias
GI upset, diarrhea
Abnormal liver enzymes
Antimicrobial class: 2nd Generation Cephalosporin
Average serum half life: Pediatrics: 1.4-1.9 hours.
Route of Elimination: 66-100% as unchanged drug in urine by both glomerular filtration and tubular secretion