Preparation and Administration

Preparation

Oseltamivir is available in 30 mg, 45 mg and 75 mg capsules, and also as a powder for oral suspension that is reconstituted to provide a final concentration of either 6 mg/mL or 12 mg/mL.

If the commercially manufactured oral suspension is not available, capsules may be opened and the contents mixed with a sweetened liquid to mask the bitter taste or a suspension can be compounded by retail pharmacies (final concentration 6 mg/ mL).

When dispensing commercially manufactured oseltamivir (Tamiflu Powder for Oral Suspension (6 mg/mL or 12 mg/mL) Hoffman-La Roche Ltd, Canada), pharmacists should ensure the units of measure on the prescription instructions match the dosing device.

Administration

Oseltamivir is administered orally without reference to meals, although administration with meals may improve gastrointestinal tolerability.