Spectrum: Local Antimicrobial Stewardship, for Alberta Children's Hospital

Cefixime

C. diff Risk

NA

Oral Bioavailability

NA

Approximate Cost

Dosing

Renal

Renally cleared, requires dosage adjustment with changes in renal funciton.

Consult a pharmacist for renal dosing.

General Pediatric

≤45 kg: 8 mg/kg/DAY divided q12-24 h
>45 kg: 400 mg once daily
Max 400 mg/DAY

General Information

Adverse Effects

Adverse Effects

  •  Allergy/rash (immediate or delayed)

  • Nausea

Pharmacology

Pharmacology

Average serum half life: Adults: 3-4 hours

Route of Elimination: Urine (50%), feces (10%)