Low
Excellent
$0.50/day
Use with caution; excretion is prolonged in patients with renal impairment. Consult with a pharmacist for dosing in renal impairment.
Prophylaxis for asplenia (children ≥3 years), PO: 500 mg/DAY divided into 2 daily doses.
Prophylaxis for asplenia (Infants and children <3 years), PO: 250 mg/DAY divided into 2 daily doses
Children >12 years and Adolescents: 375-2000 mg/DAY PO divided q6-8h or dose based on weight: 25- 75 mg/kg/DAY PO divided q6-8h.
Infants and Children <12 years: 25-75 mg/kg/DAY PO divided q6-8h. Max 2000 mg/DAY.
Streptococcal infections and therapy of documented susceptible infection not requiring parenteral therapy (i.e. upper respiratory tract)
Prophylaxis after rheumatic fever
Allergy (anaphylaxis) and other rash
Cytopenias, Positive Coombs, Eosinophilia
Serum sickness
Acute interstitial nephritis
Antimicrobial class: Penicillin
Average serum half life: No pediatric data. Adults: 30 minutes; prolonged in patients with renal impairment
Route of Elimination: Penicillin V and its metabolites are excreted in urine
