Spectrum: Local Antimicrobial Stewardship, for UCLA Health

Sinusitis

Most Likely Pathogens

Streptococci (Including S. pneumoniae)

Anaerobes

Preferred Regimen

Penicillin 20-24 million units per day as continuous infusion

OR

Ceftriaxone 2g q8h

PLUS

Metronidazole 500 mg q6h

Penicillin Anaphylaxis

ID consult advised

Vancomycin (Dosing per pharmacy)

PLUS

Metronidazole 500 mg q6h