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Guidelines
Pathogens
Antimicrobials
Treatment depends on clinical severity
C. difficile NAAT positive
Diarrhea
WBC ≥ 15,000
Increase in serum Cr > 50% from baseline
Hypotension
Ileus
Toxic megacolon or pancolitis on CT
Perforation
Need for colectomy
ICU admission for severe disease
