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Guidelines
Pathogens
Antimicrobials
Gram-negative rods including Enterobacteriaceae (e.g. Klebsiella, E. coli, Serratia)
Anaerobes (rarely)
Legionella
S. aureus (MRSA and MSSA) If concern for MRSA, consider adding vancomycin, dosed per pharmacy
Pseudomonas
(If risk factors are present)
Pseudomonas Risk Factors
Enterococci, Stenotrophomonas, and Candida species are often isolated from the sputum in hospitalized patients. In general, they should be considered to be colonizing organisms and should not be treated with antimicrobials.
