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Cough of >2 week duration, with at least one additional symptom, including fever, night sweats, weight loss, or hemoptysis
Any unexplained respiratory illness of >2 week duration in a patient at high risk for TB.
Any patient with HIV infection and unexplained cough and fever.
Any patient on anti-TNF alpha therapy with unexplained fever.
Community-acquired pneumonia which has not improved after 7 days of appropriate treatment.
Incidental findings on chest radiograph suggestive of TB (even if symptoms are minimal or absent) in a patient at high risk for TB.