Penicillin Allergy

Type 1/IgE-mediated

Symptoms:

• Urticaria

•  Angioedema

• Pruritus

• Flushing

• Anaphylaxis

• Hypotension

• Laryngeal edema

• Wheezing

Typically occurs within minutes and nearly always within 1 hour of administration.

Potentially fatal if anaphylaxis, hypotension, respiratory distress occurs

Hypotension always occurs soon after administration

Can be predicted by skin tests