Ampicillin-Sensitive
Ampicillin
Amoxicillin
Penicillin
Ampicillin-resistant, Vancomycin-sensitive
Vancomycin
Amoxicillin OK for urine isolates
VRE
Linezolid
Ampicillin or amoxicillin for uncomplicated cystitis
Add gentamicin or streptomycin when cidal activity is required (eg for endocarditis) and agents are susceptible for synergy
Ampicillin-Sensitive
Vancomycin
Linezolid
Piperacillin/tazobactam
Daptomycin
Tigecycline
Ampicillin-resistant, Vancomycin-sensitive
Linezolid
Daptomycin
VRE
Daptomycin
Tigecycline
Add gentamicin or streptomycin when cidal activity is required (eg for endocarditis) and agents are susceptible for synergy
Colonization
More likely to cause true infection in immunocompromised or after selection pressure from antimicrobial administration has eliminated other organisms
Bacteremia, endocarditis (usually subacute), intra-abdominal or hepatobiliary infection, UTI
