"Pansusceptible" isolates are sensitive to Ampicillin, cephalosporins including first generation, TMP-SMX, fluoroquinolones, and broader spectrum beta-lactams.

Resistant strains may be R to third generation cephalosporins (ESBLs), and rarely to carbapenems (i.e. carbapenemase enzymes).

Other drugs: Aminoglycosides, Aztreonam, Tigecycline, Colistin.

Fosfomycin and Nitrofurantoin for UTI only